High ping/ping spikes on FFXIV: A Realm Reborn

Used to be more stable last week (~200 - 202 ms in-game) However the ping is more unstable with Mudfish on and can reach up to 500 ms. Suggestions on how to solve this are greatly appreciated, I have tried turning on Full VPN mode but ping still spikes sometimes

Did you try to change a mudfish node based on FAQ - Nodes section?

I think you can start with the basic node mode rather than the advanced / multi-path node mode. If it works fine, you can try to test with Multi Path Mode.