Need to reopen the game when using Mudfish after playing 1 or 2 games League of Legends (Korea server)

Hi, I am using Mudfish to play League of Legends (Korea server), i got a question, when i finished 1 or 2 games, then I need to reopen the game to use Mudfish, why is this happen? mudfish problem or game problem?

Could you please confirm that it’s also same with Full VPN mode enabled?